Background: Since the patient's skin is a major source of pathogens that cause surgical-site infection, optimization of preoperative skin antisepsis may decrease postoperative infections. We hypothesized that preoperative skin cleansing with chlorhexidine-alcohol is more protective against infection than is povidone-iodine. Methods: We randomly assigned adults undergoing clean-contaminated surgery in six hospitals to preoperative skin preparation with either chlorhexidine-alcohol scrub or povidone-iodine scrub and paint. The primary outcome was any surgical-site infection within 30 days after surgery. Secondary outcomes included individual types of surgical-site infections.
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Background: Surgical site infection remains substantial problems to surgeons and patients as it increases the morbidity, mortality, length of stay, hospital cost, rate of re-admission, and rate of re-surgery. This study aims to compare the use of chlorhexidine-alcohol versus povidone-iodine for preoperative skin preparation to prevent surgical site infection. Methods: The literature search was conducted through the PubMed database on November Included studies were RCTs with the year of publication up to which compared the use of chlorhexidine-alcohol versus povidone-iodine in its effectiveness reducing surgical site infection in adult patients.
The quality of the study was assessed using Jadad Score. A meta-analysis was conducted in the included study to obtain a pooled estimate of the effect size. The evidence of heterogeneity and publication bias was also assessed. Results: Six RCTs with a total of 2, patients were included in the meta-analysis. Conclusion: Preoperative skin antisepsis with chlorhexidine is more effective than povidone-iodine in preventing surgical site infection.
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Surg Today. Chlorhexidine gluconate versus povidone iodine at cesarean delivery: a randomized controlled trial. J Matern Fetal Neonatal Med. J Med Assoc Thai. Systematic review and cost analysis comparing use of chlorhexidine with use of iodine for preoperative skin antisepsis to prevent surgical site infection. Skip to main content Skip to main navigation menu Skip to site footer. Keywords: chlorhexidine-alcohol, povidone-iodine, skin antisepsis, surgical site infection.
Abstract Background: Surgical site infection remains substantial problems to surgeons and patients as it increases the morbidity, mortality, length of stay, hospital cost, rate of re-admission, and rate of re-surgery. Efficacy and safety of povidone-iodine underscored. J Emerg Nurs. Iodine made easy.
Wounds International. How to Cite. Chlorhexidine-alcohol versus povidone-iodine as preoperative skin preparation to prevent surgical site infection: a meta-analysis. Med J Indones [Internet]. Vol 26 No 1 : March. Authors are permitted to copy and redistribute the journal's published version of the work non-commercially e. Make a Submission. Current Issue. Epigenetic: A new approach to etiology of infertility. Obesity and central obesity in Indonesia: evidence from a national health survey.
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Chlorhexidine-Alcohol Versus Povidone-Iodine for Surgical-Site Antisepsis